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BioMEMS : science and engineering perspectives / Simona Badilescu, Muthukumaran Packirisamy
| データ種別 | 電子ブック |
|---|---|
| 出版者 | Boca Raton : Taylor & Francis/CRC Press |
| 出版年 | ©2011 |
| 本文言語 | 英語 |
| 大きさ | 1 online resource (xvii, 329 pages) : illustrations (some color) |
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| 資料種別 | 機械可読データファイル |
|---|---|
| 内容注記 | Microfluidics Fluid Physics at the Microscale Methods for Enhancing Diffusive Mixing between Two Laminar Flows Controlling Flow and Transport in Microfluidic Channels Modeling Microchannel Flow Experimental Methods BioMEMS: Life Science Applications Introduction to Microarrays Microarrays Based on DNA Polymerase Chain Reaction (PCR) Protein Microarrays Cell and Tissue-Based Assays on a Chip Microreactors Micro Total Analysis Systems (μTAS) and Lab-on-a-Chip (LOC) Lab-on-a-Chip: Conclusion and Outlook Microcantilever BioMEMS 5.2.2.2. Study of Bacterial Surfaces in Aqueous Solution 5.2.2.3. AFM Study of Native Polysomes of Saccharomyces in a Physiological Buffer Solution 5.2.2.4. Single DNA Molecule Stretching Experiments by Using Chemical Force Microscopy 5.2.2.5. AFM Measurements of Competitive Binding Interactions between an Enzyme and Two Ligands 5.2.2.6. Study of Antigen-Antibody Interactions by Molecular Recognition Force Microscopy (MRFM) 5.2.2.7. Study of Cancer Alterations of Single Living Cells by AFM 5.3. X-Ray Photoelectron Spectroscopy 5.3.1. Introduction 5.3.2. X-Ray Photoelectron Spectroscopy of Biologically Important Materials 5.3.2.1. Peptide Nucleic Acids on Gold Surfaces as DNA Affinity Biosensors 5.3.2.2. Application of XPS to Probing Enzyme-Polymer Interactions at Biosensor Interfaces 5.3.2.3. Detection of Adsorbed Protein Films at Interfaces 5.4. Confocal Fluorescence Microscopy 5.4.1. Introduction 5.4.2. Biological Confocal Microscopy: Case Studies 5.4.2.1. Bioconjugated Carbon Nanotubes for Biosensor Applications 5.5. Attenuated Total Reflection (Internal Reflection) Infrared Spectroscopy 8.4. Controlling Flow and Transport in Microfluidic Channels 8.4.1. Physical Processes Underlying Electrokinetics in Electroosmosis Systems 8.4.2. Droplet Actuation Based on Marangoni Flows 8.4.3. Electrowetting 8.4.4. Thermocapillary Pumping 8.4.5. Surface Electrodeposition 8.5. Modeling Microchannel Flow 8.5.1. Introduction 8.5.2. The Finite Element Method 8.5.3. Simulation of Flow in Microfluidic Channels: Case Studies 8.5.3.1. Case 1: Silicon Microfluidic Platform for Fluorescence-Based Biosensing 8.5.3.2. Case 2: Numerical Simulation of Electroosmotic Flow in Hydrophobic Microchannels: Influence of Electrode's Position 8.5.3.3. Case 3: Prediction of Intermittent Flow Microreactor System 8.5.3.4. Case 4: Modeling of Electrowetting Flow 8.6. Experimental Methods 8.6.1. Flow Visualization at Microscale 8.6.2. Fluorescent Imaging Method 8.6.3. Particle Streak Velocimetry 8.6.4. Particle Tracking Velocimetry 8.6.5. Micro Particle Imaging Velocimetry (& mu;PIV) 8.6.6. Micro-Laser-Induced Fluorescence (& mu;LIF) Method for Shape Measurements 9.4. Protein Microarrays 9.4.1. Introduction 9.4.2. Fabrication of Protein Microarrays 9.4.3. Applications of Protein Arrays 9.5. Cell and Tissue-Based Assays on a Chip 9.6. Microreactors 9.6.1. Introduction 9.6.2. Microchannel Enzyme Reactors 9.6.3. Enzymatic Conversions: Case Studies 9.6.3.1. Glycosidase-Promoted Hydrolysis in Microchannels 9.6.3.2. Lactose Hydrolysis by Hyperthermophilic I3-Glycoside Hydrolase with Immobilized Enzyme 9.6.3.3. Photopatterning Enzymes inside Microfluidic Channels 9.6.3.4. Integrated Microfabricated Device for an Automated Enzymatic Assay 9.6.3.5. Silicon Microstructured Enzyme Reactor with Porous Silicon as the Carrier Matrix 9.6.3.6. Enzymatic Reactions Using Droplet-Based Microfluidics 9.6.4. Synthesis of Nanoparticles and Biomaterials in Microfluidic Devices 9.6.5. Microfluidic Devices for Separation |
| 一般注記 | "As technological advancements widen the scope of applications for biomicroelectromechanical systems (BioMEMS or biomicrosystems), the field continues to have an impact on many aspects of life science operations and functionalities. Because BioMEMS research and development require the input of experts who use different technical languages and come from varying disciplines and backgrounds, scientists and students can avoid potential difficulties in communication and understanding only if they possess a skill set and understanding that enables them to work at the interface of engineering and biosciences. Keeping this duality in mind throughout, BioMEMS: Science and Engineering Perspectives supports and expedites the multidisciplinary learning involved in the development of biomicrosystems. Divided into nine chapters, it starts with a balanced introduction of biological, engineering, application, and commercialization aspects of the field. With a focus on molecules of biological interest, the book explores the building blocks of cells and viruses, as well as molecules that form the self-assembled monolayers (SAMs), linkers, and hydrogels used for making different surfaces biocompatible through functionalization. The book also discusses: Different materials and platforms used to develop biomicrosystems Various biological entities and pathogens (in ascending order of complexity) The multidisciplinary aspects of engineering bioactive surfaces Engineering perspectives, including methods of manufacturing bioactive surfaces and devices Microfluidics modeling and experimentation Device level implementation of BioMEMS concepts for different applications. Because BioMEMS is an application-driven field, the book also highlights the concepts of lab-on-a-chip (LOC) and micro total analysis system (ơTAS), along with their pertinence to the emerging point-of-care (POC) and point-of-need (PON) applications"--Provided by publisher "Preface We are proud to present this book as an attempt to bridge different areas that constitute the field of biomicroelectromechanical systems (BioMEMS), often called biomicrosystems. The field of BioMEMS has been growing rapidly since the early 1990s due to the advancements in microtechnologies that could cater to the vast application requirements of bio areas. The potential of BioMEMS suits this technology for many applications, including clinical and environmental diagnostics, drug delivery, agriculture, nutrition, pharmaceuticals, chemical synthesis, etc. It is foreseen that BioMEMS will have a deep impact on many aspects of the life science operations and functionalities in the near future. Scientists and students that work in the field of BioMEMS will need to have knowledge and skills at the interface between engineering and biosciences. Development of a BioMEMS device usually involves many scientists and students from various disciplines, such as biosciences, medicine, biochemistry, engineering, physics, etc. One could anticipate many communication and understanding issues that would arise among these people with varied expertise and training. The methods, details, and languages of training are quite different for the students and researchers of engineering and biosciences. As a result, researchers and students involved with multidisciplinary projects like BioMEMS undergo an interesting and refreshing learning on multidisciplinary subjects along the project development. This book aims to support and expedite the multidisciplinary learning involved with the development of biomicrosystems, from both bioscience and engineering perspectives"--Provided by publisher Open Access English Includes bibliographical references and index Print version record |
| 著者標目 | *Badilescu, Simona. Packirisamy, Muthukumaran. |
| 件 名 | LCSH:Electronic books BSH:Electronic books LCSH:BioMEMS MESH:Biomedical Technology -- instrumentation 全ての件名で検索 MESH:Nanotechnology MESH:Biosensing Techniques BISACSH:SCIENCE -- Chemistry -- Industrial & Technical 全ての件名で検索 BISACSH:TECHNOLOGY & ENGINEERING -- Chemical & Biochemical 全ての件名で検索 FREE:BioMEMS |
| 分 類 | DC23:660.6 |
| 書誌ID | ED00001216 |
| ISBN | 9781439817001 |